منابع مشابه
Retinoid signaling regulates primitive (yolk sac) hematopoiesis.
It is known from nutritional studies that vitamin A is an important factor for normal hematopoiesis, though it has been difficult to define its precise role. The vitamin A-deficient (VAD) quail embryo provides an effective ligand "knockout" model for investigating the function of retinoids during development. The VAD embryo develops with a significant reduction in erythroid cells, which has not...
متن کاملMicroscopic aspects of the yolk sac hematopoiesis from ovine embryos
A. G. T. Pessolato , D. S. Martins , A. Galdos-Riveros , A. M. Fontes , C. E. Ambrósio , R. E. Grassi Rici, D. A. R. Magalhães, A. Castilho-Fernandes, D. T. Covas and M. A. Miglino Department of Surgery, Faculty of Veterinary Medicine and Animal Science, University of São Paulo/São Paulo, 05508270 São Paulo, Brazil. *Corresponding author: [email protected] Department of Animal Welfare, Fac...
متن کاملInitiation of hematopoiesis and vasculogenesis in murine yolk sac explants.
The blood islands of the visceral yolk sac (VYS) are the initial sites of hematopoiesis in mammals. We have developed a yolk sac explant culture system to study the process of blood cell and endothelial cell development from extraembryonic mesoderm cells. No benzidine-positive cells or beta H1-globin mRNA expression was detected at the primitive streak or neural plate stage of development (E7.5...
متن کاملYolk-sac hematopoiesis: the first blood cells of mouse and man.
OBJECTIVE To review the process of blood-cell formation in the murine and human yolk sac. DATA SOURCES Most articles were selected from the PubMed database. DATA SYNTHESIS The yolk sac is the first site of blood-cell production during murine and human ontogeny. Primitive erythroid cells originate in the yolk sac and complete their maturation, including enucleation, in the bloodstream. Thoug...
متن کاملIn vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis.
Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells. This could be due to short half-life of hematopoietic stem cells in culture or, alternatively, human embryonic stem cell-initiated hematopoiesis may be hematopoietic stem cell...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2018
ISSN: 2296-634X
DOI: 10.3389/fcell.2018.00080